Endocrine Abstracts

Introduction: Chronic hyperglycemia in type 2 diabetic patients is associated with an increased risk of micro and macrovascular complications. Therefore, glycemic control is the cornerstone of its management. The aim of this study was to evaluate glycemic control in patients with type 2 diabetes before and during COVID-19 crisis.Methods: A cross-sectional study was conducted during December 2021, in the outpatient clinic of the department of endocrinolog...

Introduction: Pallister-Hall syndrome (PHS) is a very rare congenital syndrome, and its exact prevalence is still unknown. The clinical diagnosis is usually made when a hypothalamic hamartoma is associated with polydactyly. Endocrine manifestations consist of hypopituitarism, hypopituitarism, which can affect one or more pituitary axes, and precocious puberty. Here, we report the case of an 18-year-old young man in whom the diagnosis of PHS was delayed until his hospitalizatio...

Introduction: Gynecomastia is an enlargement of male breast glandular tissue caused by an imbalance of the hormones androgens and estrogens. It can be physiological at different stages of life (birth, adolescence, senescence), caused by medication or reveal a serious pathology. The aim of our study was to evaluate the characteristics of presentation, biochemical profile, and etiology of gynecomastia.Methods: A retrospective study was conducted at the end...

Introduction: Hirsutism is described as excessive development of facial and body hair in women in androgen-dependent areas. Our aim was to determine the clinical and metabolic aspects of hirsutism and its relationship with the metabolic syndrome.Methods: We conducted a retrospective descriptive study at the endocrinology department of Rabta Hospital in Tunis. We recruited 100 women who presented with hirsutism between January 2009 and December 2020 Clini...

Introduction: Hirsutism is defined as excessive hair growth in androgen-dependent areas in women, related to an increased exposure androgen action in pilosebaceous follicles. It may be isolated, or associated to cutaneous manifestations from acne to signs of virilism. The aim of our study was to describe the therapeutic and evolutionary aspects of hirsutism.Methods: It was a retrospective study at the endocrinology department of Rabta Hospital in Tunis i...

Introduction: Primary hyperparathyroidism (PHPT) is typically characterized by elevated serum calcium associated with elevated or non-suppressed levels of parathyroid hormone (PTH). These biochemical features are both known to affect the cardiovascular (CV) system. There is a conflicting debate regarding the CV manifestations of PHPT. the aim of our study is to evaluate the cardiovascular profile in patients with PHPT.Methods: We conducted a retrospectiv...

Introduction: The development of the Covid-19 pandemic infection, which started in March 2020 in Tunisia, has impacted all medical specialties. Endocrine care professionals were part of this battle, as many patients with endocrine diseases including primary hyperparathyroidism (PHPT) were also affected by the pandemic. the aim of our study was to evaluate the Impact of the Covid19 pandemic on patients with PHPT.Methods: This is a retrospective descriptiv...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate secretion of parathyroid hormone leading to hypercalcemia. The aim of our study is to evaluate the clinical and etiological aspects of PHPT in our series.Methods: This is a retrospective descriptive study including 32 patients followed for PHPT at the endocrinology department of the military hospital of Tunisia between January 2018 and December ...

Introduction: Classification of diabetes is challenging in some cases, especially in the presence of inaugural ketosis with a negative autoimmune laboratory test. The aim of our study is to determine the role of age, body mass index (BMI), and fasting plasma C-peptide (FCP) in the classification of diabetes.Methods: This is a descriptive cross-sectional study that included 51 patients aged between 20 and 65 years hospitalized at the Endocrinology Departm...

Introduction: Dopamine agonists, mainly cabergoline and bromocriptine, represent the first-line treatment option in the management of prolactinomas. They allow prolactin normalization and tumor shrinkage. However, a subset of individuals with macroprolactinoma could exhibit a varying degree of resistance to dopamine agonists. The aim of this study was to determine the prevalence of dopamine agonist-resistance in patients with macroprolactinoma and to assess its predictive fact...